Familial Combined Hyperlipidemia: Myth or Reality?
Brouwers MCGJ, Klop B, Ribalta J, Castro Cabezas M.
Curr Atheroscler Rep. 2025 Apr 1;27(1):45. doi:10.1007/s11883-025-01289-9. PMID: 40167575; PMCID: PMC11961474.
Is cardiovascular disease in PCOS driven by MASLD?
Chen H, Simons PIHG, Brouwers MCGJ.
Trends Endocrinol Metab. 2025 May;36(5):389-391. doi:10.1016/j.tem.2024.10.005. Epub 2024 Nov 7. PMID: 39510952.
The association between sleep parameters, cognitive functioning, and markers of brain morphology: The Maastricht Study.
van Baal TL, Köhler S, Koster A, Meertens RM, Bosma H, Schram MT, Jansen JFA, Simons SO, de Galan BE, Eussen SJPM, Janssen N, Deckers K.
Sleep. 2025 Jul 28:zsaf218. doi:10.1093/sleep/zsaf218. Epub ahead of print. PMID: 40719384.
Sex-based disparities in perceived versus objective glycaemic control in type 1 diabetes: a cross-sectional cohort study.
Fuhri Snethlage CM, Smeets P, de Groen P, Rampanelli E, van Raalte DH, DeVries JH, Meijnikman AS, Siegelaar S, de Galan BE, Roep BO, Nieuwdorp M, Hanssen NMJ.
Lancet Diabetes Endocrinol. 2025 Sep;13(9):739-741. doi: 10.1016/S2213-8587(25)00136-6. Epub 2025 Jul 16. PMID: 40683296.
GLP1-agonisten en SGLT2-remmers [GLP1-agonists and SGLT2 inhibitors in the perioperative setting].
Stobbe AY, Oosterom-Eijmael MJP, de Galan BE, Hermanides J, Siegelaar SE, Hulst AH.
Ned Tijdschr Geneeskd. 2025 Jun 2;169:D8442. Dutch. PMID: 40503811.
Interaction between coffee consumption and polygenic risk score in relation to diabetes: insights from the Maastricht study.
Rao Y, Yu EY, Lin TY, Chen Y, Qin Y, Koster A, Eussen SJPM, Bosma H, Berendschot TTJM, van der Kallen CJH, van Greevenbroek MMJ, de Galan BE, Zeegers MP, Wesselius A.
Eur J Nutr. 2025 Aug 20;64(6):263. doi: 10.1007/s00394-025-03782-y. PMID: 40836180; PMCID: PMC12367902.
Aldolase B Deficient Mice Are Characterized by Hepatic Nucleotide Sugar Abnormalities.
Buziau AM, Lefeber DJ, Cassiman D, Rubio-Gozalbo ME, Kwast H, Tolan DR, Schalkwijk CG, Brouwers MCGJ.
J Inherit Metab Dis. 2025 Jan;48(1):e12836. doi: 10.1002/jimd.12836. PMID: 39727106; PMCID: PMC11672228.
Sex hormone-binding globulin as a biomarker for metabolic risk in European women with polycystic ovary syndrome.
van Bree BE, van der Heijden DMB, van Golde RJT, Brouwers MCGJ, Spaanderman MEA, Valkenburg O.
Gynecol Endocrinol. 2025 Dec;41(1):2500462. doi: 10.1080/09513590.2025.2500462. Epub 2025 May 6. PMID: 40327586.
Type 2 diabetes and depression via microvascular dysfunction, neurodegeneration, inflammation, advanced glycation end products (AGEs), and arterial stiffness.
Steens ILM, Schram MT, Houben AJHM, Berendschot TTJM, Jansen JFA, Backes WH, Koster A, Bosma H, Eussen SJPM, de Galan BE, van Sloten TT.
Diabetes Obes Metab. 2025 Sep;27(9):4847-4858. doi: 10.1111/dom.16527. Epub 2025 Jun 19. PMID: 40536118; PMCID: PMC12326927.
Carnitine supplementation improves insulin sensitivity and skeletal muscle acetylcarnitine formation in patients with type 2 diabetes.
Op den Kamp-Bruls YMH, Op den Kamp YJM, Veeraiah P, Zapata Perez R, Phielix E, Havekes B, Schaart G, Kornips E, Berendsen BRB, Virmani A, Wildberger JE, Houtkooper RH, Hesselink MKC, Schrauwen P, Schrauwen-Hinderling VB.
Diabetes Obes Metab. 2025 May;27(5):2864-2877. doi: 10.1111/dom.16298. Epub 2025 Feb 28. PMID: 40019115; PMCID: PMC11965010.
Novel Insights Into Gyrate Atrophy of the Choroid and Retina (GACR): A Cohort Study.
Balfoort BM, Van den Broeck F, Boon CJF, Brouwers MCGJ, Diederen RMH, Dhillon P; GACR “Bird's Eye View” Consortium; van Hasselt PM, Jaeger B, Karuntu JS, Rennings AJM, van Spronsen FJ, Timmer C, Wagenmakers MAEM, De Zaeytijd J, Leroy BP, Schulze A, van Karnebeek CD, Brands MM.
J Inherit Metab Dis. 2025 Jan;48(1):e12842. doi: 10.1002/jimd.12842. PMID: 39761806; PMCID: PMC11703598.
Steatotic liver disease interacts with a polygenic risk score for triglyceride clearance to impact the risk of hypertriglyceridaemia: The Maastricht Study.
Ren Z, Wesselius A, Kooi ME, van Greevenbroek M, Dagnelie P, Berendschot TTJM, Kroon AA, Houben AJHM, Stehouwer CDA, Brouwers MCGJ.
Diabetologia. 2025 Oct;68(10):2217-2226. doi: 10.1007/s00125-025-06479-3. Epub 2025 Jun 27. PMID: 40579639; PMCID: PMC12423141.
Treatment preferences of adult patients with hereditary fructose intolerance: A discrete choice experiment.
Janssen LEF, Hiligsmann M, Timmer C, van der Ploeg LMC, Kerckhove KV, Cox T, Heras JL, Cassiman D, Brouwers MCGJ.
Mol Genet Metab. 2025 Aug;145(4):109169. doi: 10.1016/j.ymgme.2025.109169. Epub 2025 Jun 7. PMID: 40505295.
The effects of dietary fructose on blood pressure are modified by the food matrix.
van Oeteren MAJ, de Groot DM, Buziau AM, Scheijen JLJM, van de Waarenburg MPH, Kroon AA, Eussen SJPM, Dagnelie PC, van Greevenbroek MMJ, Houben AJHM, Meex SJR, Schalkwijk CG, Brouwers MCGJ.
Clin Nutr. 2025 Dec;55:134-140. doi: 10.1016/j.clnu.2025.10.017. Epub 2025 Nov 1. PMID: 41202663.
Glucose variability measured by continuous glucose monitoring is associated with skin autofluorescence: the Maastricht Study.
Dimitropoulou NM, Eussen SJPM, Schalkwijk CG, de Galan BE.
Diabetologia. 2025 Sep;68(9):1937-1946. doi: 10.1007/s00125-025-06469-5. Epub 2025 Jun 20. PMID: 40542279; PMCID: PMC12361322.
Radiotherapy-induced Hypothalamic-Pituitary axis dysfunction in adult Brain, head and neck and skull base tumor patients - A systematic review and Meta-Analysis.
Paulissen JMJ, Zegers CML, Houben RM, Hofstede D, Kars M, van Santen HM, Hoebers FJP, Ruysscher DKM, Eekers DBP.
Clin Transl Radiat Oncol. 2024 Dec 14;51:100900. doi: 10.1016/j.ctro.2024.100900. PMID: 39801827; PMCID: PMC11721507.
Effects of insulin-induced hypoglycaemia on cardiac function in people with type 1 and type 2 diabetes and people without diabetes.
Fabricius TW, Verhulst C, Svensson CH, Wienberg M, Duijnhouwer AL, Tack CJ, Kristensen PL, de Galan BE, Pedersen-Bjergaard U; Hypo‐RESOLVE consortium.
Diabetes Obes Metab. 2025 May;27(5):2768-2776. doi: 10.1111/dom.16283. Epub 2025 Mar 5. PMID: 40045554; PMCID: PMC11964998.
Association between recent real-life exposure to hypoglycaemia and cognitive function during hypoglycaemia in people with type 1 diabetes: Findings from the Hypo-RESOLVE clamp study..
Svensson CH, Fabricius TW, Verhulst C, Tack CJ, Kristensen PL, de Galan BE, Pedersen-Bjergaard U; Hypo‐RESOLVE consortium.
Diabetes Obes Metab. 2025 Oct;27(10):5455-5463. doi: 10.1111/dom.16587. Epub 2025 Jul 11. PMID: 40642831; PMCID: PMC12409216.
Erfelijke metabole ziekten bij volwassenen [Inherited metabolic disorders in adults:growing patient numbers, advanced diagnostic tools and new treatment modalities].
Langeveld M, Brouwers MCGJ, van Dussen L, Koens LH, Langendonk JGL, Janssen MCH.
Ned Tijdschr Geneeskd. 2025 Jul 15;169:D8476. Dutch. PMID: 40673355.
Effects of glucose and fructose supplementation on serum sex hormone-binding globulin and testosterone levels: Post-hoc analysis of a double-blind randomized controlled trial.
Chen H, Simons PIHG, Simons N, van de Waarenburg MPH, Bons JAP, van der Ploeg EMC, Feskens EJM, Schalkwijk CG, Brouwers MCGJ.
Clin Nutr ESPEN. 2025 Oct;69:384-388. doi: 10.1016/j.clnesp.2025.07.1123. Epub 2025 Jul 26. PMID: 40721209.
Study protocol for exploring diabetes numeracy and health literacy across Europe (EDUCATE): A multicentre cross-sectional study.
den Brok EJ, Hornborg-Svensson C, Dimitropoulou NM, Broeng-Mikkelgaard S, Olsen MT, Rahman LA, Papathanail I, Wiede A, Peters J, Mertens PR, Zikou E, Karamanakos G, Athanasopoulos S, Mitrakou A, Makrilakis K, van Kuijk SMJ, Mougiakakou S, van Greevenbroek MMJ, Pedersen-Bjergaard U, de Galan BE, Dingena CF; MELISSA consortium.
Diabet Med. 2025 Nov;42(11):e70140. doi: 10.1111/dme.70140. Epub 2025 Sep 18. PMID: 40963466; PMCID: PMC12535314.
The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes.
Ali N, van Erp S, Kramers C, Tack CJ, de Galan BE.
Clin Pharmacol Ther. 2025 Nov 12. doi: 10.1002/cpt.70130. Epub ahead of print. PMID: 41221687.
Fructose restriction has beneficial effects on adipose tissue distribution but not on serum adipokine levels: Post-hoc analysis of a double-blind randomized controlled trial.
van Oeteren MAJ, Simons N, Simons PIHG, van de Waarenburg MPH, Kooi ME, Feskens EJM, van der Ploeg EMCL, Van den Eynde MDG, Houben AJHM, Schalkwijk CG, Brouwers MCGJ.
Clin Obes. 2025 Feb;15(1):e12714. doi: 10.1111/cob.12714. Epub 2024 Oct 28. PMID: 39468417; PMCID: PMC11706758.
Evaluating the feasibility of study methods for a future trial-based economic evaluation of a multistage shared decision-making program for type 2 diabetes mellitus: Protocol for a cluster-randomized controlled pilot study.
Tichler A, Hertroijs DFL, van Mastrigt GAPG, Brouwers MCGJ, Ruwaard D, Elissen AMJ.
PLoS One. 2025 Aug 5;20(8):e0300944. doi: 10.1371/journal.pone.0300944. PMID: 40763135; PMCID: PMC12324081.
Socioeconomic position and type 2 diabetes: Examining the mediating role of social cohesion-The Maastricht Study.
Albers JD, Koster A, Sezer B, Meisters R, Chan JA, Wesselius A, Schram MT, de Galan BE, Lakerveld J, Bosma H.
Soc Sci Med. 2025 Jul;376:118046. doi: 10.1016/j.socscimed.2025.118046. Epub 2025 Apr 15. PMID: 40286503.
Diabetes and incident stroke and mediation by microvascular dysfunction: Pooled analysis of three population-based studies.
Steens ILM, Ji Y, Sedaghat S, Pankow J, Klein BEK, Cotch MF, McClelland RL, Hayden KM, Hughes TM, Bancks MP, Houben AJHM, Kroon AA, Koster A, Bosma H, Berendschot TTJM, de Galan BE, van Sloten TT.
Diabetes Obes Metab. 2025 Apr;27(4):2299-2304. doi: 10.1111/dom.16217. Epub 2025 Jan 30. PMID: 39888145; PMCID: PMC11885081.
Reconciling the apparently contrasting observational and genetic evidence on the association between MASLD and cardiovascular disease.
Brouwers MCGJ.
J Hepatol. 2025 May;82(5):e269-e270. doi: 10.1016/j.jhep.2024.11.042. Epub 2024 Nov 30. PMID: 39617131.
User evaluation of the Hypo-METRICS app: A tool for real-time symptom reporting of hypoglycaemia.
Cigler M, Søholm U, Broadley M, Pouwer F, Abbink EJ, Ali N, de Galan BE, Renard E, Evans M, Bøggild Brøsen JM, Pedersen-Bjergaard U, Mc Crimmon RJ, Heller S, Caunt S, Amiel SA, Divilly P, Zaremba N, Choudhary P, Mader JK; Hypo‐RESOLVE consortium.
Diabet Med. 2025 Dec 30:e70185. doi: 10.1111/dme.70185. Epub ahead of print. PMID: 41472376.
Liver fat content is not elevated in people with type 1 diabetes: the Maastricht Study.
Dimitropoulou NM, Beran M, Eussen SJPM, Dingena CF, Dagnelie PC, van der Kallen CJH, Koster A, van Greevenbroek MMJ, Brouwers MCGJ, Schram MT, de Galan BE.
Diabetologia. 2026 Feb;69(2):364-373. doi: 10.1007/s00125-025-06597-y. Epub 2025 Nov 7. PMID: 41198917.
β-Cell Mass in Individuals With and Without Postbariatric Hypoglycemia After Roux-en-Y Gastric Bypass.
Tokgöz S, Deden LN, Hofboer A, Hazebroek EJ, de Boer H, van Bon AC, Meijer RI, de Galan BE, Tack CJ, Boss M, Gotthardt M.
Diabetes. 2025 Dec 1;74(12):2301-2306. doi: 10.2337/db25-0572. PMID: 41066755; PMCID: PMC12645168.
Development of a patient decision aid for type 2 diabetes mellitus: a patient-centered approach.
Tichler A, Hertroijs DFL, Ruwaard D, Brouwers MCGJ, Elissen AMJ.
BMC Prim Care. 2025 Mar 22;26(1):81. doi: 10.1186/s12875-025-02772-7. PMID: 40121397; PMCID: PMC11929313.
Activation of the HPA Axis Does Not Explain Nonresponsiveness to GLP-1R Agonist Treatment in Individuals With Type 2 Diabetes.
Tokgöz S, Boss M, Jansen TJP, Meijer R, Frielink C, van Bon AC, Tack CJ, de Galan BE, Gotthardt M.
Diabetes. 2025 Feb 1;74(2):212-222. doi: 10.2337/db24-0463. PMID: 39561332; PMCID: PMC11755685.
Four-Dimensional Dual-Energy Computed Tomography-Derived Parameters and Their Correlation with Thyroid Gland Functional Status.
Scheepers MHMC, Al-Difaie ZJJ, Bouvy ND, Havekes B, Postma AA.
Tomography. 2025 Feb 26;11(3):22. doi: 10.3390/tomography11030022. PMID: 40137563; PMCID: PMC11946797.
Associations of blood pressure with retinal arteriolar narrowing and urinary albumin excretion are modified by prediabetes: the Maastricht study.
Wang K, Kroon AA, de Galan BE, Berendschot TTJM, Schram MT, Houben AJHM, van Greevenbroek MMJ.
J Hypertens. 2025 Dec 18. doi: 10.1097/HJH.0000000000004225. Epub ahead of print. PMID: 41411631.
Recurrent hypoglycaemia promotes cardiomyopathy and cardiac vulnerability in a rodent model of type 1 diabetes.
Forteath C, Merchant HJ, Kocherry C, Murdoch CE, Kerr J, Gallagher JR, Evans ML, Thorens B, Pedersen-Bjergaard U, de Galan BE, McCrimmon RJ, McNeilly AD; Hypo-RESOLVE Consortium.
Diabetologia. 2026 Feb;69(2):515-528. doi: 10.1007/s00125-025-06574-5. Epub 2025 Nov 10. PMID: 41212210; PMCID: PMC12779658.
Reallocating morning physical activity to later-day activity and its association with type 2 diabetes incidence: The Maastricht Study.
Chong MY, Eussen SJPM, van der Velde JHPM, de Galan BE, Savelberg HHCM, Bosma H, Bours MJL, Weijenberg MP, Koster A.
Diabetes Obes Metab. 2026 Jan 13. doi: 10.1111/dom.70438. Epub ahead of print. PMID: 41527700.
Exploring the role of class stigma in socioeconomic inequalities in type 2 diabetes: The Maastricht Study.
Sezer B, Albers J, Meisters R, Schram MT, de Galan BE, van der Kallen C, van Greevenbroek M, Dagnelie P, Koster A, Bosma H.
J Health Psychol. 2026 Jan 13:13591053251395856. doi: 10.1177/13591053251395856. Epub ahead of print. PMID: 41528758.
Safety and efficacy of pharmacological inhibition of ketohexokinase in hereditary fructose intolerance.
Koene EJ, Buziau AM, Cassiman D, Cox TM, Bons J, Scheijen JL, Schalkwijk CG, Meex SJ, Saxena AR, Esler WP, Schrauwen-Hinderling VB, Schrauwen P, Brouwers MCGJ.
J Clin Invest. 2025 Feb 11;135(6):e187376. doi: 10.1172/JCI187376. PMID: 39932807; PMCID: PMC11910217.