Relationship between NAFLD and coronary artery disease: A Mendelian randomization study.
Ren Z, Simons PIHG, Wesselius A, Stehouwer CDA, Brouwers MCGJ.
Hepatology. 2023 Jan 1;77(1):230-238. doi: 10.1002/hep.32534. Epub 2022 May 18. PMID: 35441719; PMCID: PMC9970021.

Genetic Susceptibility to Nonalcoholic Fatty Liver Disease and Risk for Pancreatic Cancer: Mendelian Randomization.
King SD, Veliginti S, Brouwers MCGJ, Ren Z, Zheng W, Setiawan VW, Wilkens LR, Shu XO, Arslan AA, Beane Freeman LE, Bracci PM, Canzian F, Du M, Gallinger SJ, Giles GG, Goodman PJ, Haiman CA, Kogevinas M, Kooperberg C, LeMarchand L, Neale RE, Visvanathan K, White E, Albanes D, Andreotti G, Babic A, Berndt SI, Brais LK, Brennan P, Buring JE, Rabe KG, Bamlet WR, Chanock SJ, Fuchs CS, Gaziano JM, Giovannucci EL, Hackert T, Hassan MM, Katzke V, Kurtz RC, Lee IM, Malats N, Murphy N, Oberg AL, Orlow I, Porta M, Real FX, Rothman N, Sesso HD, Silverman DT, Thompson IM, Wactawski-Wende J, Wang X, Wentzensen N, Yu H, Zeleniuch-Jacquotte A, Yu K, Wolpin BM, Duell EJ, Li D, Hung RJ, Perdomo S, McCullough ML, Freedman ND, Patel AV, Peters U, Riboli E, Sund M, Tjønneland A, Zhong J, Van Den Eeden SK, Kraft P, Risch HA, Amundadottir LT, Klein AP, Stolzenberg-Solomon RZ, Antwi SO.
Cancer Epidemiol Biomarkers Prev. 2023 Sep 1;32(9):1265-1269. doi: 10.1158/1055-9965.EPI-23-0453. PMID: 37351909; PMCID: PMC10529823.

Cotadutide promotes glycogenolysis in people with overweight or obesity diagnosed with type 2 diabetes.
Parker VER, Robertson D, Erazo-Tapia E, Havekes B, Phielix E, de Ligt M, Roumans KHM, Mevenkamp J, Sjoberg F, Schrauwen-Hinderling VB, Johansson E, Chang YT, Esterline R, Smith K, Wilkinson DJ, Hansen L, Johansson L, Ambery P, Jermutus L, Schrauwen P.
Nat Metab. 2023 Dec;5(12):2086-2093. doi: 10.1038/s42255-023-00938-0. Epub 2023 Dec 8. PMID: 38066113; PMCID: PMC10730390.

Cardiovascular Implications of Metabolic Dysfunction-Associated Fatty Liver Disease.
Ren Z, Wesselius A, Stehouwer CDA, Brouwers MCGJ.
Endocrinol Metab Clin North Am. 2023 Sep;52(3):459-468. doi: 10.1016/j.ecl.2023.01.002. Epub 2023 Mar 8. PMID: 37495337.

Resistance Training: a Strong Case for People With Type 1 Diabetes?
Siegelaar SE, de Galan BE.
J Clin Endocrinol Metab. 2023 Jun 16;108(7):e491-e492. doi: 10.1210/clinem/dgad037. PMID: 36690414.

Relationship between educational attainment and non-alcoholic fatty liver disease: A two-sample Mendelian randomization study.
Ren Z, Wesselius A, Stehouwer CDA, Brouwers MCGJ.
Dig Liver Dis. 2024 Apr;56(4):565-570. doi: 10.1016/j.dld.2023.11.040. Epub 2023 Dec 15. PMID: 38104027.

Traditional lifestyle factors partly mediate the association of socioeconomic position with intrahepatic lipid content: The Maastricht study.
Ren Z, Bosma H, Wesselius A, Eussen SJPM, Kooi ME, van der Kallen CJH, Koster A, van Greevenbroek MMJ, Dagnelie P, Stehouwer CDA, Brouwers MCGJ.
JHEP Rep. 2023 Jul 18;5(11):100855. doi: 10.1016/j.jhepr.2023.100855. PMID: 37771365; PMCID: PMC10522893.

Oral magnesium supplementation does not affect insulin sensitivity in people with insulin-treated type 2 diabetes and a low serum magnesium: a randomized controlled trial.
Drenthen LCA, de Baaij JHF, Rodwell L, van Herwaarden AE, Tack CJ, de Galan BE.
Diabetologia. 2024 Jan;67(1):52-61. doi: 10.1007/s00125-023-06029-9. Epub 2023 Nov 3. PMID: 37922013; PMCID: PMC10709477.

Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial.
van Beek SMM, Bruls YMH, Vanweert F, Fealy CE, Connell NJ, Schaart G, Moonen-Kornips E, Jörgensen JA, Vaz FM, Smeets ETHC, Joris PJ, Gemmink A, Houtkooper RH, Hesselink MKC, Bengtsson T, Havekes B, Schrauwen P, Hoeks J.
Nat Commun. 2023 Jan 12;14(1):173. doi: 10.1038/s41467-023-35798-5. PMID: 36635304; PMCID: PMC9835033.

Effects of the sodium-glucose cotransporter 2 inhibitor dapagliflozin on substrate metabolism in prediabetic insulin resistant individuals: A randomized, double-blind crossover trial.
Veelen A, Andriessen C, Op den Kamp Y, Erazo-Tapia E, de Ligt M, Mevenkamp J, Jörgensen JA, Moonen-Kornips E, Schaart G, Esterline R, Havekes B, Oscarsson J, Schrauwen-Hinderling VB, Phielix E, Schrauwen P.
Metabolism. 2023 Mar;140:155396. doi: 10.1016/j.metabol.2022.155396. Epub 2022 Dec 30. PMID: 36592688.

Association of physical activity with endothelial dysfunction among adults with and without chronic kidney disease: The Maastricht Study.
Bellos I, Marinaki S, Lagiou P, Boletis IN, Stehouwer CDA, van Greevenbroek MMJ, Eussen SJPM, de Galan BE, Savelberg HHCM, Koster A, Wesselius A, Benetou V.
Atherosclerosis. 2023 Oct;383:117330. doi: 10.1016/j.atherosclerosis.2023.117330. Epub 2023 Oct 5. PMID: 37837705.

Diagnostic Performance of Magnetic Resonance Imaging for Parathyroid Localization of Primary Hyperparathyroidism: A Systematic Review.
Scheepers MHMC, Al-Difaie Z, Brandts L, Peeters A, Winkens B, Al-Taher M, Engelen SME, Lubbers T, Havekes B, Bouvy ND, Postma AA.
Diagnostics (Basel). 2023 Dec 22;14(1):25. doi: 10.3390/diagnostics14010025. PMID: 38201335; PMCID: PMC10802165.

Quality of life of adult patients with hereditary fructose intolerance.
Janssen LEF, Cassiman D, Brouwers MCGJ.
Mol Genet Metab. 2023 Nov;140(3):107701. doi: 10.1016/j.ymgme.2023.107701. Epub 2023 Sep 20. PMID: 37757598.

Development of tools to facilitate the diagnosis of hereditary fructose intolerance.
Panis B, Janssen LEF, Lefeber DJ, Simons N, Rubio-Gozalbo ME, Brouwers MCGJ.
JIMD Rep. 2023 Jul 27;64(5):353-359. doi: 10.1002/jmd2.12379. PMID: 37701328; PMCID: PMC10494505.

Serum sex hormone-binding globulin is a mediator of the association between intrahepatic lipid content and type 2 diabetes: the Maastricht Study.
Simons PIHG, Valkenburg O, van de Waarenburg MPH, van Greevenbroek MMJ, Kooi ME, Jansen JFA, Schalkwijk CG, Stehouwer CDA, Brouwers MCGJ.
Diabetologia. 2023 Jan;66(1):213-222. doi: 10.1007/s00125-022-05790-7. Epub 2022 Sep 17. PMID: 36114428; PMCID: PMC9729158.

Importance of beta cell mass for glycaemic control in people with type 1 diabetes.
Jansen TJP, Brom M, Boss M, Buitinga M, Tack CJ, van Meijel LA, de Galan BE, Gotthardt M.
Diabetologia. 2023 Feb;66(2):367-375. doi: 10.1007/s00125-022-05830-2. Epub 2022 Nov 17. PMID: 36394644; PMCID: PMC9669532.

Replacing Foods with a High-Glycemic Index and High in Saturated Fat by Alternatives with a Low Glycemic Index and Low Saturated Fat Reduces Hepatic Fat, Even in Isocaloric and Macronutrient Matched Conditions.
Basset-Sagarminaga J, Roumans KHM, Havekes B, Mensink RP, Peters HPF, Zock PL, Mutsert R, Borén J, Lindeboom L, Schrauwen P, Schrauwen-Hinderling VB.
Nutrients. 2023 Feb 1;15(3):735. doi: 10.3390/nu15030735. PMID: 36771441; PMCID: PMC9920748.

Daily Physical Activity Patterns and Their Associations with Cardiometabolic Biomarkers: The Maastricht Study.
Leskinen T, Lima Passos V, Dagnelie PC, Savelberg HHCM, de Galan BE, Eussen SJPM, Stehouwer CDA, Stenholm S, Koster A.
Med Sci Sports Exerc. 2023 May 1;55(5):837-846. doi: 10.1249/MSS.0000000000003108. Epub 2022 Dec 27. PMID: 36728772; PMCID: PMC10090323.

Quantifying postprandial glucose responses using a hybrid modeling approach: Combining mechanistic and data-driven models in The Maastricht Study.
Erdős B, van Sloun B, Goossens GH, O'Donovan SD, de Galan BE, van Greevenbroek MMJ, Stehouwer CDA, Schram MT, Blaak EE, Adriaens ME, van Riel NAW, Arts ICW.
PLoS One. 2023 Jul 27;18(7):e0285820. doi: 10.1371/journal.pone.0285820. PMID: 37498860; PMCID: PMC10374070.

Fall in prevalence of impaired awareness of hypoglycaemia in individuals with type 1 diabetes.
Ali N, El Hamdaoui S, Schouwenberg BJ, Tack CJ, de Galan BE.
Diabet Med. 2023 Apr;40(4):e15042. doi: 10.1111/dme.15042. Epub 2023 Jan 21. PMID: 36645139.

Hypoglycaemia induces a sustained pro-inflammatory response in people with type 1 diabetes and healthy controls.
Verhulst CEM, van Heck JIP, Fabricius TW, Stienstra R, Teerenstra S, McCrimmon RJ, Tack CJ, Pedersen-Bjergaard U, de Galan BE; Hypo-RESOLVE consortium.
Diabetes Obes Metab. 2023 Nov;25(11):3114-3124. doi: 10.1111/dom.15205. Epub 2023 Jul 24. PMID: 37485887.

Both short and long sleep durations are associated with type 2 diabetes, independent from traditional lifestyle risk factors-The Maastricht Study.
Albers JD, Meertens RM, Savelberg HHCM, Köhler S, Wesselius A, Schram MT, Stehouwer CDA, de Galan BE, van Greevenbroek MMJ, van der Kallen CJH, Eussen SJPM, Bosma H, Schaper NC, Koster A.
Sleep Health. 2023 Oct;9(5):733-741. doi: 10.1016/j.sleh.2023.06.009. Epub 2023 Aug 10. PMID: 37573207.

Relation of Change or Substitution of Low- and No-Calorie Sweetened Beverages With Cardiometabolic Outcomes: A Systematic Review and Meta-analysis of Prospective Cohort Studies.
Buziau AM, Blokland GAM, Schalkwijk CG, Scheijen JLJM, Simons PIHG, Eussen SJPM, Dagnelie PC, van Greevenbroek MMJ, Wesselius A, Stehouwer CDA, Brouwers MCGJ. Comment on Lee et al.
Diabetes Care 2022;45:1917-1930. Diabetes Care. 2023 Apr 1;46(4):e97-e98. doi: 10.2337/dc22-1930. PMID: 36952606.

Preferred Conversation Topics with Respect to Treatment Decisions Among Individuals with Type 2 Diabetes.
Tichler A, Hertroijs DFL, Ruwaard D, Brouwers MCGJ, Hiligsmann M, de Jong JD, Elissen AMJ.
Patient Prefer Adherence. 2023 Mar 17;17:719-729. doi: 10.2147/PPA.S397647. PMID: 36960182; PMCID: PMC10029372.

A prolonged fast improves overnight substrate oxidation without modulating hepatic glycogen in adults with and without nonalcoholic fatty liver: A randomized crossover trial.
Roumans KHM, Veelen A, Andriessen C, Mevenkamp J, Kornips E, Veeraiah P, Havekes B, Peters HPF, Lindeboom L, Schrauwen P, Schrauwen-Hinderling VB.
Obesity (Silver Spring). 2023 Mar;31(3):757-767. doi: 10.1002/oby.23676. Epub 2023 Feb 9. PMID: 36756887.

No insulin degludec dose adjustment required after aerobic exercise for people with type 1 diabetes: the ADREM study.
Drenthen LCA, Ajie M, Abbink EJ, Rodwell L, Thijssen DHJ, Tack CJ, de Galan BE.
Diabetologia. 2023 Jun;66(6):1035-1044. doi: 10.1007/s00125-023-05893-9. Epub 2023 Mar 7. PMID: 36879098; PMCID: PMC9988601.

Can virtual non-contrast imaging replace true non-contrast imaging in multiphase scanning of the neck region?
Al-Difaie Z, Scheepers MH, Bouvy ND, Engelen S, Havekes B, Postma AA.
Acta Radiol Open. 2023 Sep 25;12(8):20584601231205159. doi: 10.1177/20584601231205159. PMID: 37767056; PMCID: PMC10521284.

Chronic hyperglycaemia increases the vulnerability of the hippocampus to oxidative damage induced during post-hypoglycaemic hyperglycaemia in a mouse model of chemically induced type 1 diabetes.
McNeilly AD, Gallagher JR, Evans ML, de Galan BE, Pedersen-Bjergaard U, Thorens B, Dinkova-Kostova AT, Huang JT, Ashford MLJ, McCrimmon RJ; Hypo-RESOLVE Consortium.
Diabetologia. 2023 Jul;66(7):1340-1352. doi: 10.1007/s00125-023-05907-6. Epub 2023 Apr 4. Erratum in: Diabetologia. 2024 Aug;67(8):1724. doi: 10.1007/s00125-024-06188-3. PMID: 37015997; PMCID: PMC10244284.

Impact of sedentary behaviour on glucose concentration in people with type 1 diabetes.
Drenthen LCA, Ajie M, Teerenstra S, Abbink EJ, Bakker EA, Thijssen DHJ, Tack CJ, de Galan BE.
Diabetes Obes Metab. 2024 Mar;26(3):1142-1143. doi: 10.1111/dom.15397. Epub 2023 Dec 11. PMID: 38073428.

Daily unstructured physical activity affects mean glucose, occurrence of hypoglycaemia and glucose variability in people with type 1 diabetes.
Drenthen LCA, Ajie M, Bakker EA, Abbink EJ, Thijssen DHJ, Tack CJ, de Galan BE.
Diabetes Obes Metab. 2023 Dec;25(12):3837-3840. doi: 10.1111/dom.15277. Epub 2023 Sep 18. PMID: 37722974.

(Pre)diabetes and a higher level of glycaemic measures are continuously associated with corneal neurodegeneration assessed by corneal confocal microscopy: the Maastricht Study.
Mokhtar SBA, van der Heide FCT, Oyaert KAM, van der Kallen CJH, Berendschot TTJM, Scarpa F, Colonna A, de Galan BE, van Greevenbroek MMJ, Dagnelie PC, Schalkwijk CG, Nuijts RMMA, Schaper NC, Kroon AA, Schram MT, Webers CAB, Stehouwer CDA.
Diabetologia. 2023 Nov;66(11):2030-2041. doi: 10.1007/s00125-023-05986-5. Epub 2023 Aug 17. PMID: 37589735; PMCID: PMC10541833.

Associations between plasma sulfur amino acids and specific fat depots in two independent cohorts: CODAM and The Maastricht Study.
Tore EC, Elshorbagy AK, Bakers FCH, Brouwers MCGJ, Dagnelie PC, Eussen SJPM, Jansen JFA, Kooi ME, Kusters YHAM, Meex SJR, Olsen T, Refsum H, Retterstøl K, Schalkwijk CG, Stehouwer CDA, Vinknes KJ, van Greevenbroek MMJ.
Eur J Nutr. 2023 Mar;62(2):891-904. doi: 10.1007/s00394-022-03041-4. Epub 2022 Nov 2. PMID: 36322288; PMCID: PMC9941263.

High diabetes-specific distress among adults with type 1 diabetes and impaired awareness of hypoglycaemia despite widespread use of sensor technology.
Ali N, El Hamdaoui S, Nefs G, Walburgh Schmidt JWJ, Tack CJ, de Galan BE.
Diabet Med. 2023 Sep;40(9):e15167. doi: 10.1111/dme.15167. Epub 2023 Jun 27. PMID: 37347681.

Monitoring β-Cell Survival After Intrahepatic Islet Transplantation Using Dynamic Exendin PET Imaging: A Proof- of-Concept Study in Individuals With Type 1 Diabetes.
Jansen TJP, Buitinga M, Boss M, Nijhoff MF, Brom M, de Galan BE, van der Graaf M, van Koeverden S, Vantyghem MC, Beron A, Pattou F, Engelse MA, Velikyan I, Eriksson O, de Koning EJP, Gotthardt M.
Diabetes. 2023 Jul 1;72(7):898-907. doi: 10.2337/db22-0884. PMID: 37068261.

Hyperglycemia and glucose variability are associated with worse survival in mechanically ventilated COVID-19 patients: the prospective Maastricht Intensive Care Covid Cohort.
van Herpt TTW, van Rosmalen F, Hulsewé HPMG, van der Horst-Schrivers ANA, Driessen M, Jetten R, Zelis N, de Galan BE, van Kuijk SMJ, van der Horst ICC, van Bussel BCT.
Diabetol Metab Syndr. 2023 Dec 6;15(1):253. doi: 10.1186/s13098-023-01228-1. PMID: 38057908; PMCID: PMC10698889.

Determinants and mediating mechanisms of quality of life and disease- specific symptoms among thyroid cancer patients: the design of the WaTCh study.
Mols F, Schoormans D, Netea-Maier R, Husson O, Beijer S, Van Deun K, Zandee W, Kars M, Wouters van Poppel PCM, Simsek S, van Battum P, Kisters JMH, de Boer JP, Massolt E, van Leeuwaarde R, Oranje W, Roerink S, Vermeulen M, van de Poll-Franse L.
Thyroid Res. 2023 Jul 10;16(1):23. doi: 10.1186/s13044-023-00165-5. PMID: 37424010; PMCID: PMC10332086.

Diagnostic Value of Four-Dimensional Dynamic Computed Tomography for Primary Hyperparathyroidism in Patients with Low Baseline Parathyroid Hormone Levels.
Al-Difaie Z, Scheepers MHMC, Engelen SME, Havekes B, Bouvy ND, Postma AA.
Diagnostics (Basel). 2023 Aug 8;13(16):2621. doi: 10.3390/diagnostics13162621. PMID: 37627880; PMCID: PMC10453623

Effects of fructose added to an oral glucose tolerance test on plasma glucose excursions in healthy adults.
Buziau AM, Scheijen JLJM, Stehouwer CDA, Schalkwijk CG, Brouwers MCGJ.
Metabol Open. 2023 May 12;18:100245. doi: 10.1016/j.metop.2023.100245. PMID: 37251289; PMCID: PMC10209703.

Long-Term Evaluation of Spinal Cord Stimulation in Patients With Painful Diabetic Polyneuropathy: An Eight-to-Ten-Year Prospective Cohort Study.
Zuidema X, van Daal E, van Geel I, de Geus TJ, van Kuijk SMJ, de Galan BE, de Meij N, Van Zundert J.
Neuromodulation. 2023 Jul;26(5):1074-1080. doi: 10.1016/j.neurom.2022.12.003. Epub 2022 Dec 31. PMID: 36587999.

Association of type 2 diabetes according to the number of risk factors within the recommended range with incidence of major depression and clinically relevant depressive symptoms: a prospective analysis.
van Gennip ACE, Schram MT, Köhler S, Kroon AA, Koster A, Eussen SJPM, de Galan BE, van Sloten TT, Stehouwer CDA.
Lancet Healthy Longev. 2023 Feb;4(2):e63-e71. doi: 10.1016/S2666-7568(22)00291-4. PMID: 36738746.

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