Improved glucometrics in people with type 1 diabetes 1 year into the COVID-19 pandemic.
Ali N, El Hamdaoui S, Nefs G, Tack CJ, De Galan BE.
BMJ Open Diabetes Res Care. 2022 May;10(3):e002789. doi: 10.1136/bmjdrc-2022-002789. PMID: 35606020; PMCID: PMC9125382.

Three weeks of time-restricted eating improves glucose homeostasis in adults with type 2 diabetes but does not improve insulin sensitivity: a randomised crossover trial.
Andriessen C, Fealy CE, Veelen A, van Beek SMM, Roumans KHM, Connell NJ, Mevenkamp J, Moonen-Kornips E, Havekes B, Schrauwen-Hinderling VB, Hoeks J, Schrauwen P..
Diabetologia. 2022 Oct;65(10):1710-1720. doi: 10.1007/s00125-022-05752-z. Epub 2022 Jul 25. PMID: 35871650; PMCID: PMC9477920.

The 12-Item Hypoglycemia Impact Profile (HIP12): psychometric validation of a brief measure of the impact of hypoglycemia on quality of life among adults with type 1 or type 2 diabetes.
Broadley M, Chatwin H, Søholm U, Amiel SA, Carlton J, De Galan BE, Hendrieckx C, McCrimmon RJ, Skovlund SE, Pouwer F, Speight J; Hypo-RESOLVE Consortium.
BMJ Open Diabetes Res Care. 2022 Aug;10(4):e002890. doi: 10.1136/bmjdrc-2022-002890. PMID: 35977753; PMCID: PMC9389129.

Intrahepatic lipid content is independently associated with soluble E-selectin levels: The Maastricht study.
Brouwers MCGJ, Simons N, Kooi ME, de Ritter R, van Dongen MCJM, Eussen SJPM, Bekers O, Kooman J, van Greevenbroek MMJ, van der Kallen CJH, Schram MT, Schaper NC, Schalkwijk CG, Stehouwer CDA.
Dig Liver Dis. 2022 Aug;54(8):1038-1043. doi: 10.1016/j.dld.2022.01.130. Epub 2022 Feb 5. PMID: 35135742.

Fructose 1-phosphate, an evolutionary signaling molecule of abundancy.
Brouwers MCGJ.
Trends Endocrinol Metab. 2022 Oct;33(10):680-689. doi: 10.1016/j.tem.2022.07.007. Epub 2022 Aug 19. PMID: 35995682.

Fructose Intake From Fruit Juice and Sugar-Sweetened Beverages Is Associated With Higher Intrahepatic Lipid Content: The Maastricht Study.
Buziau AM, Eussen SJPM, Kooi ME, van der Kallen CJH, van Dongen MCJM, Schaper NC, Henry RMA, Schram MT, Dagnelie PC, van Greevenbroek MMJ, Wesselius A, Bekers O, Meex SJR, Schalkwijk CG, Stehouwer CDA, Brouwers MCGJ.
Diabetes Care. 2022 May 1;45(5):1116-1123. doi: 10.2337/dc21-2123. PMID: 35158374.

Unmet support needs relating to hypoglycaemia among adults with type 1 diabetes: Results of a multi-country web-based qualitative study.
Chatwin H, Broadley M, Hendrieckx C, Carlton J, Heller S, Amiel SA, de Galan BE, Hermanns N, Finke-Groene K, Speight J, Pouwer F; Hypo-RESOLVE Consortium.
Diabet Med. 2022 Jan;39(1):e14727. doi: 10.1111/dme.14727. Epub 2021 Oct 27. PMID: 34668230; PMCID: PMC9298379.

FDG Uptake and Expression of Immunohistochemical Markers Related to Glycolysis, Hypoxia, and Proliferation in Indeterminate Thyroid Nodules.
de Koster EJ, van Engen-van Grunsven ACH, Bussink J, Frielink C, de Geus-Oei LF, Kusters B, Peters H, Oyen WJG, Vriens D; EFFECTS trial study group.
Mol Imaging Biol. 2023 Jun;25(3):483-494. doi: 10.1007/s11307-022-01776-4. Epub 2022 Oct 17. PMID: 36253663; PMCID: PMC10172288.

Low-Iodine Diet of 4 Days Is Sufficient Preparation for 131I Therapy in Differentiated Thyroid Cancer Patients.
Dekker BL, Links MH, Muller Kobold AC, Swart-Busscher LG, Kars M, Bons JAP, Brouwers AH, Links TP, van der Horst-Schrivers ANA.
J Clin Endocrinol Metab. 2022 Jan 18;107(2):e604-e611. doi: 10.1210/clinem/dgab691. PMID: 34534327; PMCID: PMC8764339.

Second-Trimester Constituents of the Metabolic Syndrome and Pregnancy Outcome: An Observational Cohort Study.
Ellerbrock J, Hubers E, Ghossein-Doha C, Schiffer V, Alers RJ, Jorissen L, Neer JV, Zelis M, Janssen E, Landewé-Cleuren S, Haarlem AV, Kramer B, Spaanderman M.
Nutrients. 2022 Jul 18;14(14):2933. doi: 10.3390/nu14142933. PMID: 35889890; PMCID: PMC9325303.

Anxiety and cognitive functioning in the Maastricht study: A cross-sectional population study.
Gulpers BJA, Verhey FRJ, Eussen SJPM, Schram MT, de Galan BE, van Boxtel MPJ, Stehouwer CDA, Köhler S.
J Affect Disord. 2022 Dec 15;319:570-579. doi: 10.1016/j.jad.2022.09.072. Epub 2022 Sep 23. PMID: 36162695.

High childhood serum triglyceride concentrations associate with hepatocellular adenoma development in patients with glycogen storage disease type Ia.
Haring MPD, Peeks F, Oosterveer MH, Brouwers MCGJ, Hollak CEM, Janssen MCH, Langendonk JG, Rennings AJM, Wagenmakers MAEM, Verkade HJ, Derks TGJ, de Meijer VE.
JHEP Rep. 2022 May 29;4(8):100512. doi: 10.1016/j.jhepr.2022.100512. PMID: 35811762; PMCID: PMC9263528.

Divergent remodeling of the skeletal muscle metabolome over 24 h between young, healthy men and older, metabolically compromised men.
Harmsen JF, van Weeghel M, Parsons R, Janssens GE, Wefers J, van Moorsel D, Hansen J, Hoeks J, Hesselink MKC, Houtkooper RH, Schrauwen P.
Cell Rep. 2022 Dec 13;41(11):111786. doi: 10.1016/j.celrep.2022.111786. PMID: 36516749.

The influence of bright and dim light on substrate metabolism, energy expenditure and thermoregulation in insulin-resistant individuals depends on time of day.
Harmsen JF, Wefers J, Doligkeit D, Schlangen L, Dautzenberg B, Rense P, van Moorsel D, Hoeks J, Moonen-Kornips E, Gordijn MCM, van Marken Lichtenbelt WD, Schrauwen P.
Diabetologia. 2022 Apr;65(4):721-732. doi: 10.1007/s00125-021-05643-9. Epub 2022 Feb 2. PMID: 35106618; PMCID: PMC8894310.

Importance of beta cell mass for glycaemic control in people with type 1 diabetes.
Jansen TJP, Brom M, Boss M, Buitinga M, Tack CJ, van Meijel LA, de Galan BE, Gotthardt M.
Diabetologia. 2023 Feb;66(2):367-375. doi: 10.1007/s00125-022-05830-2. Epub 2022 Nov 17. PMID: 36394644; PMCID: PMC9669532.

Effects of fructose restriction on blood pressure: Secondary analysis of a double-blind randomized controlled trial.
Janssen LEF, Simons N, Simons PIHG, Schaper NC, Feskens EJM, van der PloegLMC, Van den Eynde MDG, Schalkwijk CG, Houben AJHM, Stehouwer CDA, Brouwers MCGJ.
Clin Nutr ESPEN. 2022 Oct;51:97-103. doi: 10.1016/j.clnesp.2022.07.009. Epub 2022 Jul 30. PMID: 36184254.

The impact of hypoglycaemia in children and adolescents with type 1 diabetes on parental quality of life and related outcomes: A systematic review.
Jensen MV, Broadley M, Speight J, Chatwin H, Scope A, Cantrell A, Heller S, de Galan BE, Hendrieckx C, Pouwer F; of the Hypo-RESOLVE consortium.
Pediatr Diabetes. 2022 May;23(3):390-405. doi: 10.1111/pedi.13308. Epub 2022 Jan 23. PMID: 34981624.

Novel insights in intestinal and hepatic fructose metabolism: from mice to men.
Koene E, Schrauwen-Hinderling VB, Schrauwen P, Brouwers MCGJ.
Curr Opin Clin Nutr Metab Care. 2022 Sep 1;25(5):354-359. doi: 10.1097/MCO.0000000000000853. Epub 2022 Jul 16. PMID: 35838297.

Daily Physical Activity Patterns and Their Associations with Cardiometabolic Biomarkers: The Maastricht Study.
Leskinen T, Lima Passos V, Dagnelie PC, Savelberg HHCM, DE Galan BE, Eussen SJPM, Stehouwer CDA, Stenholm S, Koster A.
Med Sci Sports Exerc. 2023 May 1;55(5):837-846. doi: 10.1249/MSS.0000000000003108. Epub 2022 Dec 27. PMID: 36728772; PMCID: PMC10090323.

Changes in quality of life following hypoglycaemia in adults with type 2 diabetes: A systematic review of longitudinal studies.
Matlock KA, Broadley M, Hendrieckx C, Clowes M, Sutton A, Heller SR, de Galan BE, Pouwer F, Speight J; Hypo-RESOLVE consortium.
Diabet Med. 2022 Jan;39(1):e14706. doi: 10.1111/dme.14706. Epub 2021 Oct 7. PMID: 34596292; PMCID: PMC9293422.

Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism.
Op den Kamp YJM, Gemmink A, de Ligt M, Dautzenberg B, Kornips E, Jorgensen JA, Schaart G, Esterline R, Pava DA, Hoeks J, Schrauwen-Hinderling VB, Kersten S, Havekes B, Koves TR, Muoio DM, Hesselink MKC, Oscarsson J, Phielix E, Schrauwen P.
Mol Metab. 2022 Dec;66:101620. doi: 10.1016/j.molmet.2022.101620. Epub 2022 Oct 21. PMID: 36280113; PMCID: PMC9636471.

Long-term survival in patients with gastroenteropancreatic neuroendocrine neoplasms: A population-based study.
Poleé IN, Hermans BCM, van der Zwan JM, Bouwense SAW, Dercksen MW, Eskens FALM, Havekes B, Hofland J, Kerkhofs TMA, Klümpen HJ, Latten-Jansen LM, Speel EM, Verburg FA, Walenkamp AME, Geurts SME, de Vos-Geelen J.
Eur J Cancer. 2022 Sep;172:252-263. doi: 10.1016/j.ejca.2022.06.003. Epub 2022 Jul 6. PMID: 35803176.

Circulating N-Acetylaspartate does not track brain NAA concentrations, cognitive function or features of small vessel disease in humans.
Rebelos E, Daniele G, Campi B, Saba A, Koskensalo K, Ihalainen J, Saukko E, Nuutila P, Backes WH, Jansen JFA, Dagnelie PC, Köhler S, de Galan BE, van Sloten TT, Stehouwer CDA, Ferrannini E.
Sci Rep. 2022 Jul 7;12(1):11530. doi: 10.1038/s41598-022-15670-0. PMID: 35798828; PMCID: PMC9262942.

Progressive diastolic dysfunction in survivors of pediatric differentiated thyroid carcinoma.
Reichert AD, Nies M, Tissing WJE, Muller Kobold AC, Klein Hesselink MS, Brouwers AH, Havekes B, van den Heuvel-Eibrink MM, van der Pal HJH, Plukker JTM, van Santen HM, Corssmit EPM, Netea-Maier RT, Peeters RP, van Dam EWCM, Burgerhof JGM, van der Meer P, Bocca G, Links TP.
Eur J Endocrinol. 2022 Sep 12;187(4):497-505. doi: 10.1530/EJE-22-0094. PMID: 35947635.

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study.
Ren Z, Simons PIHG, Wesselius A, Stehouwer CDA, Brouwers MCGJ.
Hepatology. 2023 Jan 1;77(1):230-238. doi: 10.1002/hep.32534. Epub 2022 May 18. PMID: 35441719; PMCID: PMC9970021.

Detection of differentiated thyroid carcinoma in exhaled breath with an electronic nose.
Scheepers MHMC, Al-Difaie ZJJ, Wintjens AGWE, Engelen SME, Havekes B, Lubbers T, Coolsen MME, van der Palen J, van Ginhoven TM, Vriens M, Bouvy ND.
J Breath Res. 2022 Jun 21;16(3). doi: 10.1088/1752-7163/ac77a9. PMID: 35688135.

A realist evaluation to identify targets to improve the organization of compression therapy for deep venous thrombosis- and chronic venous disease patients.
Schreurs RHP, Joore MA, De Bruijn-Geraets DP, Ten Cate H, Ten Cate-Hoek AJ.
PLoS One. 2022 Aug 8;17(8):e0272566. doi: 10.1371/journal.pone.0272566. PMID: 35939451; PMCID: PMC9359574.

Development of a Consensus-Based Cross-Domain Protocol for the Management of Elastic Compression Stocking Therapy in Patients With Deep Venous Thrombosis and Chronic Venous Disease: A Modified Delphi Study.
Schreurs RHP, Joore MA, Ten Cate H, Ten Cate-Hoek AJ.
Front Cardiovasc Med. 2022 May 19;9:891364. doi: 10.3389/fcvm.2022.891364. PMID: 35665269; PMCID: PMC9160232.

Causal relationship between polycystic ovary syndrome and coronary artery disease: A Mendelian randomisation study.
Simons PIHG, Cornelissen MEB, Valkenburg O, Onland-Moret NC, van der Schouw YT, Stehouwer CDA, Burgess S, Brouwers MCGJ.
Clin Endocrinol (Oxf). 2022 Apr;96(4):599-604. doi: 10.1111/cen.14593. Epub 2021 Sep 15. PMID: 34524719; PMCID: PMC7612926.

Association between de novo lipogenesis susceptibility genes and coronary artery disease.
Simons PIHG, Valkenburg O, Stehouwer CDA, Brouwers MCGJ.
Nutr Metab Cardiovasc Dis. 2022 Dec;32(12):2883-2889. doi: 10.1016/j.numecd.2022.09.003. Epub 2022 Sep 15. PMID: 36182335.

Serum sex hormone-binding globulin levels are reduced and inversely associated with intrahepatic lipid content and saturated fatty acid fraction in adult patients with glycogen storage disease type 1a.
Simons PIHG, Valkenburg O, Telgenkamp I, van der Waaij KM, de Groot DM, Veeraiah P, Bons JAP, Derks TGJ, Schalkwijk CG, Schrauwen-Hinderling VB, Stehouwer CDA, Brouwers MCGJ.
J Endocrinol Invest. 2022 Jun;45(6):1227-1234. doi: 10.1007/s40618-022-01753-2. Epub 2022 Feb 7. PMID: 35132570; PMCID: PMC9098618.

Serum sex hormone-binding globulin is a mediator of the association between intrahepatic lipid content and type 2 diabetes: the Maastricht Study.
Simons PIHG, Valkenburg O, van de Waarenburg MPH, van Greevenbroek MMJ, Kooi ME, Jansen JFA, Schalkwijk CG, Stehouwer CDA, Brouwers MCGJ.
Diabetologia. 2023 Jan;66(1):213-222. doi: 10.1007/s00125-022-05790-7. Epub 2022 Sep 17. PMID: 36114428; PMCID: PMC9729158.

Associations between plasma sulfur amino acids and specific fat depots in two independent cohorts: CODAM and The Maastricht Study.
Tore EC, Elshorbagy AK, Bakers FCH, Brouwers MCGJ, Dagnelie PC, Eussen SJPM, Jansen JFA, Kooi ME, Kusters YHAM, Meex SJR, Olsen T, Refsum H, Retterstøl K, Schalkwijk CG, Stehouwer CDA, Vinknes KJ, van Greevenbroek MMJ.
Eur J Nutr. 2023 Mar;62(2):891-904. doi: 10.1007/s00394-022-03041-4. Epub 2022 Nov 2. PMID: 36322288; PMCID: PMC9941263.

Use of sodium-glucose co-transporter 2 inhibitors, changes in body mass index and risk of fracture: A population-based cohort study.
van Dalem J, Werkman NCC, van den Bergh JP, Rossi B, Viggers R, Eastell R, Burden AM, Stehouwer CDA, Klungel OH, Brouwers MCGJ, Driessen JHM.
Diabetes Res Clin Pract. 2022 Aug;190:109993. doi: 10.1016/j.diabres.2022.109993. Epub 2022 Jul 14. PMID: 35842030.

(Pre)diabetes, glycemia, and daily glucose variability are associated with retinal nerve fiber layer thickness in The Maastricht Study.
van der Heide FCT, Foreman YD, Franken IWM, Henry RMA, Kroon AA, Dagnelie PC, Eussen SJPM, Berendschot TTJM, Schouten JSAG, Webers CAB, Schram MT, van der Kallen CJH, van Greevenbroek MMJ, Wesselius A, Schalkwijk CG, Schaper NC, Brouwers MCGJ, Stehouwer CDA.
Sci Rep. 2022 Oct 22;12(1):17750. doi: 10.1038/s41598-022-22748-2. PMID: 36273238; PMCID: PMC9587985.

Lactate infusion as therapeutical intervention: a scoping review.
van Gemert LA, de Galan BE, Wevers RA, Ter Heine R, Willemsen MA.
Eur J Pediatr. 2022 Jun;181(6):2227-2235. doi: 10.1007/s00431-022-04446-3. Epub 2022 Mar 18. PMID: 35304646; PMCID: PMC9110504.

Effect of lactate administration on cerebral blood flow during hypoglycemia in people with type 1 diabetes.
van Meijel LA, van Asten JJA, Grandjean J, Heerschap A, Tack CJ, van der Graaf M, Wiegers EC, de Galan BE.
BMJ Open Diabetes Res Care. 2022 Mar;10(2):e002401. doi: 10.1136/bmjdrc-2021-002401. PMID: 35321886; PMCID: PMC8943734

Neurocognitive outcome and mental health in children with tyrosinemia type 1 and phenylketonuria: A comparison between two genetic disorders affecting the same metabolic pathway.
van Vliet K, van Ginkel WG, Jahja R, Daly A, MacDonald A, Santra S, De Laet C, Goyens PJ, Vara R, Rahman Y, Cassiman D, Eyskens F, Timmer C, Mumford N, Gissen P, Bierau J, van Hasselt PM, Wilcox G, Morris AAM, Jameson EA, de la Parra A, Arias C, Garcia MI, Cornejo V, Bosch AM, Hollak CEM, Rubio-Gozalbo ME, Brouwers MCGJ, Hofstede FC, de Vries MC, Janssen MCH, van der Ploeg AT, Langendonk JG, Huijbregts SCJ, van Spronsen FJ.
J Inherit Metab Dis. 2022 Sep;45(5):952-962. doi: 10.1002/jimd.12528. Epub 2022 Jun 30. PMID: 35722880; PMCID: PMC9540223.

Effects of the sodium-glucose cotransporter 2 inhibitor dapagliflozin on substrate metabolism in prediabetic insulin resistant individuals: A randomized, double-blind crossover trial.
Veelen A, Andriessen C, Op den Kamp Y, Erazo-Tapia E, de Ligt M, Mevenkamp J, Jörgensen JA, Moonen-Kornips E, Schaart G, Esterline R, Havekes B, Oscarsson J, Schrauwen-Hinderling VB, Phielix E, Schrauwen P.
Metabolism. 2023 Mar;140:155396. doi: 10.1016/j.metabol.2022.155396. Epub 2022 Dec 30. PMID: 36592688.

Consistent Effects of Hypoglycemia on Cognitive Function in People With or Without Diabetes. Diabetes Care.
Verhulst CEM, Fabricius TW, Nefs G, Kessels RPC, Pouwer F, Teerenstra S, Tack CJ, Broadley MM, Kristensen PL, McCrimmon RJ, Heller S, Evans ML, Pedersen-Bjergaard U, de Galan BE.
Diabetes Care. 2022 Sep 1;45(9):2103-2110. doi: 10.2337/dc21-2502. PMID: 35876660; PMCID: PMC9472511.

Glycaemic thresholds for counterregulatory hormone and symptom responses to hypoglycaemia in people with and without type 1 diabetes: a systematic review.
Verhulst CEM, Fabricius TW, Teerenstra S, Kristensen PL, Tack CJ, McCrimmon RJ, Heller S, Evans ML, Amiel SA, Pedersen-Bjergaard U, de Galan BE; Hypo-RESOLVE consortium.
Diabetologia. 2022 Oct;65(10):1601-1612. doi: 10.1007/s00125-022-05749-8. Epub 2022 Jul 22. PMID: 35867127; PMCID: PMC9477942.

Sustained Proinflammatory Effects of Hypoglycemia in People With Type 2 Diabetes and in People Without Diabetes.
Verhulst CEM, van Heck JIP, Fabricius TW, Stienstra R, Teerenstra S, McCrimmon RJ, Tack CJ, Pedersen-Bjergaard U, de Galan BE.
Diabetes. 2022 Dec 1;71(12):2716-2727. doi: 10.2337/db22-0246. PMID: 35848804; PMCID: PMC9750956.

Long-term Evaluation of Spinal Cord Stimulation in Patients With Painful Diabetic Polyneuropathy: An Eight-to-Ten-Year Prospective Cohort Study.
Zuidema X, van Daal E, van Geel I, de Geus TJ, van Kuijk SMJ, de Galan BE, de Meij N, Van Zundert J.
Neuromodulation. 2022 Dec 30:S1094-7159(22)01403-9. doi: 10.1016/j.neurom.2022.12.003. Epub ahead of print. PMID: 36587999.

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